Publications

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D Liu, L Albergante, D Horn, TJ Newman. Faster Growth With Shorter Antigens Explains A VSG Hierarchy During African Trypanosome Infections: A Feint Attack By Parasites. SR, 2018.

L Albergante, EM Mirkes, H Chen, A Martin, L Faure, E Barillot, L Pinello, AN Gorban, A Zinovyev. Robust And Scalable Learning Of Complex Dataset Topologies Via Elpigraph. preprint, 2018.

S Palmer, L Albergante, CC Blackburn, TJ Newman. Reply to Jiménez-Alonso et al., Schooling and Zhao, and Mortazavi: Further discussion on the immunological model of carcinogenesis. PNAS, 2018.

H Chen, L Albergante, JY Hsu, CA Lareau, G Lo Bosco, J Guan, S Zhou, AN Gorban, DE Bauer, MJ Aryee, DM Langenau, A Zinovyev, JD Buenrostro, GC Yuan, L Pinello. STREAM: Single-cell Trajectories Reconstruction, Exploration And Mapping of omics data. Preprint, 2018.

S Palmer, L Albergante, CC Blackburn, TJ Newman. Thymic involution and rising disease incidence with age. PNAS, 2018.

PDF Ageing immune system may explain age-related cancer risk increase Immune system could be key in fight against cancer Could ageing immune systems be a better predictor of cancer than genetic mutations? Aging immune system may explain age-related cancer risk increase Ageing immune system ‘key to cancer development risk’ Our aging immune system explains cancer, not genetic mutations says new study Tumori e invecchiamento: il ruolo sottovalutato del sistema immunitario Cancer Incidence can Increase with Aging Immune System Models Suggest that Declining T Cell Production is the Primary Reason for Age-Related Increases in Cancer Risk Aging immune system may explain age-related cancer risk increase Immune system an important cancer predictor Ageing immune system linked to cancer Men with ageing immune system more susceptible to cancer: Research Could ageing immune systems be a better predictor of cancer than genetic mutations? Aging immune system may explain age-related cancer risk increase Aging immune system may explain age-related cancer risk increase Aging immune system may explain age-related cancer risk increase

L Albergante, D Liu, TJ Newman. Universal attenuators and their interactions with feedback loops in gene regulatory networks. NAR, 2017.

A Moreno, JT Carrington, L Albergante, M Al Mamun, EJ Haagensen, ES Komseli, VG Gorgoulis, TJ Newman, JJ Blow. Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells. PNAS, 2016.

PDF Joint research shows daughter cells resolve their mother’s unreplicated DNA

L Albergante, M Al Mamun, A Moreno, JT Carrington, JJ Blow, TJ Newman. Inevitability and containment of replication errors for eukaryotic genome lengths spanning megabase to gigabase. PNAS, 2016.

PDF Joint research shows daughter cells resolve their mother’s unreplicated DNA

L Albergante, D Liu, S Palmer, TJ Newman. Insights into Biological Complexity from Simple Foundations. Biophysics of Infection, 2016.

L Albergante, JHS Dayal, TJ Newman, AP South. Quantitation of multiclonality in control and drug-treated tumour populations using high-throughput analysis of karyotypic heterogeneity. Conv. Sc. Phys. Onc., 2015.

L Albergante, JJ Blow, TJ Newman. Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks. eLife, 2014.

PDF Biological networks: interdisciplinary collaboration sheds light on what makes cells robust

M Tinti, K Dissanayake, S Synowsky, L Albergante, C MacKintosh. Identification of 2R-ohnologue gene families displaying the same mutation-load skew in multiple cancers. Open Bio., 2014.

PDF Study of DNA and datasets gives fresh insight into cancer

L Albergante, J Timmis, L Beattie, PM Kaye. A Petri net model of granulomatous inflammation: implications for IL-10 mediated control of Leishmania donovani infection. PLOS Comp Bio, 2013.

L Albergante. Automatic management of forums via artificial immune systems. IJAACS, 2011.

M Casu, L Albergante. Identity in the Real World. Thinking Machines and the Philosophy of Computer Science: Concepts and Principles, 2010.

L Albergante, J Timmis, P Andrews, L Beattie, PM Kaye. A Petri Net Model of Granulomatous Inflammation. ICARIS 2010, 2010.

L Albergante. Wireless discussion forums: Automatic management via artificial immune systems. SPECTS 2008, 2008.